Table 3.

Prognostic factors for OS in patients with visceral metastases, selected by cox univariable and multivariable analysis.

Variants	Number	Prognostic factors for OS[1]
		Univariable analysis		Multivariable analysis
		HR[2] (95%CI[3])	p-Value	HR (95%CI)	p-Value
Age
Lower than median age (<71)	43	Ref.	–	Ref.	–
Higher than median age (> =71)	47	2.187 (1.057-4.524)	*0.035	2.754 (1.259-6.024)	*0.011
Site of visceral metastasis
Lung	61	Ref.	–	Ref.	–
Liver	21	2.609 (1.217-5.597)	*0.014	2.418 (1.106-5.289)	*0.027
Both lung and liver	8	2.465 (0.826-7.353)	0.11	2.528 (0.840-7.608)	0.099
Clinical T stage
T = 2	29	Ref.	–
T = 3 or 4	61	1.451 (0.651-3.236)	0.36
Clinical N stage
N = 0	24	Ref.	–
N = 1	66	0.718 (0.340-1.518)	0.39
PSA level
Lower than median PSA (<79.62)	37	Ref.	–
Higher than median PSA (> =79.62)	38	1.180 (0.545-2.557)	0.67
Missing	15	–	–
Gleason score
6-7	15	Ref.	–
8-10	47	0.906 (0.334-2.460)	0.85
Missing	28	–	–
[18F]FDG uptake in primary tumor
Lower than median SUVmax (<6.10)	44	Ref.	–
Higher than median SUVmax (> =6.10)	46	1.140 (0.567-2.296)	0.71
[18F]FDG uptake in metastatic lesion
Lower than median SUVmax (<2.85)	45	Ref.	–	Ref.	–
Higher than median SUVmax (> =2.85)	45	3.150 (1.485-6.682)	**0.003	4.399 (1.984-9.753)	***<0.001

[1] OS: overall survival.

[2] HR: hazard ratio.

[3] 95% CI: 95% confidence interval.

[4] Significance level set at p < 0.05. *p < 0.05, **p < 0.01, ***p < 0.001.