Table 4.

Prognostic factors for OS in patients with bone metastases, Selected by Cox Univariable and Multivariable analysis.

Variants	Number	Prognostic factors for OS[1]
		Univariable analysis		Multivariable analysis
		HR[2] (95%CI[3])	p-Value	HR (95%CI)	p-Value
Age
Lower than median age (<72)	81	Ref.	–
Higher than median age (> =72)	96	0.644 (0.334-1.243)	0.188
Clinical T stage
T = 2	104	Ref.	–
T = 3 or 4	73	1.707 (0.887-3.283)	0.109
Clinical N stage
N = 0	65	Ref.	–
N = 1	112	1.859 (0.896-3.860)	0.096
PSA level
Lower than median PSA (<63.61)	71	Ref.	–
Higher than median PSA (> =63.61)	71	1.873 (0.897-3.911)	0.095
Missing	35	–	–
Gleason score
6-7	50	Ref.	–
8-10	82	1.429 (0.592-3.446)	0.427
Missing	45	–	–
[18F]FDG uptake in primary tumor
Lower than median SUVmax (<4.50)	87	Ref.	–
Higher than median SUVmax (> =4.50)	90	1.010 (0.524-1.946)	0.976
[18F]FDG uptake in metastatic lesion
Lower than median SUVmax (<5.50)	86	Ref.	–	Ref.	–
Higher than median SUVmax (> =5.50)	91	5.340 (2.219-12.849)	***<0.001	5.340 (2.219-12.849)	***<0.001

[1] OS: overall survival.

[2] HR: hazard ratio.

[3] 95% CI: 95% confidence interval.

[4] Significance level set at p < 0.05. *p < 0.05, **p < 0.01, ***p < 0.001.