Fig. 4.

Minocycline suppressed sevoflurane-induced elevation of inflammatory cytokines in the hippocampus of aged rats. The levels of TNF-α, IL-1β, and IL-6 in rat hippocampus were examined by Western blot analysis. Densitometry analysis was performed using β-actin as the internal control. This figure shows the representative images of all the experimental rats, and the values are expressed as the mean ± SD (n = 6 for each group). Compared with control group, **P < 0.01; compared with sevoflurane group, ^# P < 0.05, ^## P < 0.01