FIG. 1.

Virus titers of V3000 and V3043 in 129Sv/Ev mouse tissues. Six- to 8-week-old 129Sv/Ev mice were inoculated s.c. in the LRFP with 10³ PFU of V3000 (solid bars) or V3043 (hatched bars). At the indicated times p.i., three mice per group were sacrificed and the following tissues were harvested: DLN (A), spleen (B), serum (C), and brain (D). Virus titers were determined by plaque assay of BHK-21 cells. The values are the geometric mean titers (log₁₀ PFU/milliliter or gram) of three mice. Error bars represent standard deviations. The lower limit of detection is indicated by a broken line. ∗, all samples had virus titers below the limit of detection; ∗∗, one out of three samples had virus liters above the limit of detection.