Table 1. PLSCR1 variants associated with severe COVID-19 in a GWAS [25,26].
| GWAS p-value | rsID | Genomic Coordinate (GRCh38) | Nucleotide Change | Gene | Functional Consequence |
|---|---|---|---|---|---|
| 7.52 × 10−7 | rs116553931 | chr3:146430956 | C:T | PLSCR2 | intron variant |
| 1.08 × 10−7 | rs454645 | chr3:146514682 | C:T | PLSCR1 | Downstream transcript variant |
| 5.43 × 10−8 | rs343320 | chr3:146517122 | G:A | PLSCR1 | p.His262Tyr |
| 8.21 × 10−8 | rs343318 | chr3:146518204 | T:C | PLSCR1 | intron variant |
| 1.52 × 10−7 | rs343317 | chr3:146518374 | A:G | PLSCR1 | intron variant |
| 1.00 × 10−7 | rs186910 | chr3:146520241 | A:G | PLSCR1 | intron variant |
| 1.13 × 10−7 | rs173150 | chr3:146520256 | A:T | PLSCR1 | intron variant |
| 1.35 × 10−7 | rs71302408 | chr3:146520389 | T:C | PLSCR1 | intron variant |
| 7.06 × 10−8 | rs343316 | chr3:146521151 | A:G | PLSCR1 | intron variant |
| 4.64 × 10−8 | rs343314 | chr3:146522652 | C:T | PLSCR1 | intron variant |
| 7.46 × 10−8 | rs343312 | chr3:146522970 | G:A | PLSCR1 | intron variant |