Figure 6. Metformin promotes lipophagy in hepatic cells by inhibiting TNFα and mTORC1 via actuation of TTP through the Sirtuin 1/AMPK signaling trail.

TNF α: Tumor necrosis factor-alpha; TTP: tristetraprolin; mTORC1: mammalian target of rapamycin complex 1; AMPK: AMP-activated protein kinase.

This figure was drawn using the premium version of BioRender (https://biorender.com/), accessed on September 25, 2024, with the agreement license number VX27CL769T [10].

Image credit: Rahnuma Ahmad