FIG. 6.

Plasma variants from IVAG-inoculated monkeys (Fig. 8) mixed with the SIVmac1A11 reference variant (lane 1) or the endpoint dilution of the virus stock (VSEV; lanes 7 and 13). The 21743 and 23224 variants are shown alone (lanes 2 and 3), mixed with the 1A11 variant (lanes 4 and 5), and mixed together (lane 6). Monkeys 21743 and 23224 were infected with the same envelope variant, based on the formation of a homoduplex when the two variants were mixed (lane 6). Mixtures of VSEV with plasma variants (lanes 8 to 12) indicate that monkey 24762 was infected with the most common variant in the stock (lane 12), but that multiple V1-V2 variants were transmitted to four other monkeys (lanes 8 to 11).