Fig. 6.
Sialin maintains colon epithelial barrier-related proteins and the proliferation of colon epithelial cells. a Immunofluorescence staining of E-cadherin (green), Sialin (red), PCNA (red), MUC2 (red) and DAPI (blue) in the colonic tissues in the group of K14-cre; Slc17a5fl/+ control and K14-cre; Slc17a5fl/fl mice. Scale bar: 100 μm. Data were shown as mean ± SD (n = 5 per group). ***Indicates significance at P < 0.001, *P < 0.05. b Western blot analysis of ZO-1, E-cadherin, Claudin 1 and Sialin expression in colon tissues of K14-cre; Slc17a5fl/+ and K14-cre; Slc17a5fl/fl mice (n = 5 per group). Data were shown as mean ± SD