TABLE 4.

Adjusted odds ratio (OR) from interrupted time series logistic regression for emergency department (ED) encounters before (January 1, 2018‒December 31, 2018), immediately after (January 1, 2019‒31, 2019), and 1 year after (February 1, 2019‒December 31, 2019) implementation of California naloxone law.

	Any opioid poison			Any non‐opioid poison			Any naloxone prescribed at discharge
	OR	LCI	UCI	OR	LCI	UCI	OR	LCI	UCI
Pre‐policy trend	0.99	0.96	1.02	1.02	0.98	1.05	1.60	1.45	1.76
Immediate change in level post‐policy	0.93	0.69	1.27	1.21	0.91	1.62	13.23	10.26	17.06
Change in trend between pre‐ and post‐policy	1.02	0.98	1.07	0.97	0.93	1.01	0.62	0.56	0.68
No. of observations	1,110,127	1,110,127	1,089,211

Note: All analyses controlled for age group (10‒15 [reference group], 16‒22, 23‒34, 35‒50, and >50), sex (female [reference group] and male), race/ethnicity (NH White [reference group], NH Black, Hispanic, NH Asian/Pacific Islanders, and others), and Charlson score (none [reference group], 1, 2, and 3+). The first two analyses for opioid poison and non‐opioid poison excluded 25 visits, while last analysis for naloxone prescribed at discharge excluded 23 visits due to missing data on sex.

Abbreviations: LCI, lower confidence interval; UCI, upper confidence interval.