Figure 7.

Integrated nomograms and its performance to predict 1-year, 3-year, 5-year overall survival (OS) for patients with gastric cancer from the TCGA-STAD, ACRG, YUSH, SMC, and KRIBB cohorts. (A) Multivariate analysis of DFS for the clinicopathologic characteristics and gsTLS; (B) Multivariate analysis of OS for the clinicopathologic characteristics and gsTLS; (C) A gsTLS-based nomogram was established to predict the prognosis of patients with gastric cancer. (D) Calibration of the nomogram in terms of agreement between the predicted and observed probabilities for 1-year, 3-year, and 5-year survival. (E) Decision curve analysis of OS. (F) The gsTLS of different nomogram status. (G) Kaplan–Meier plots of OS according to the output score of the nomogram. (H) Time-dependent receiver operator characteristic (ROC) curves of the nomogram in the ACRG, YUSH, SMC, and KRIBB cohorts. DFS, disease-free survival; gsTLS, gene signature of tertiary lymphoid structures; OS, overall survival; TCGA-STAD, The Cancer Genome Atlas-stomach adenocarcinoma.