Table 2.

Outcome of the study population, in terms of RR, PFS and OS

		1 Treatment line (N = 50)	>1 Treatment line (N = 63)	Total (N = 113)	p value
RR	PR	21 (42.0%)	10 (15.9%)	31 (27.4%)	0.0160
	SD	13 (26.0%)	26 (41.3%)	39 (34.5%)
	PD	16 (32.0%)	27 (42.9%)	43 (38.1%)
PFS (months)	Median (95% CI)	9.0 (5.6, 15.4)	5.5 (4.1, 6.8)	6.3 (5.3, 8.1)	0.0200
Two years PFS	% (95% CI)	22.0 (13.0, 37.1)	12.7 (6.6, 37.1)	16.8 (11.2, 25.3)
OS (months)	Median (95% CI)	13.2 (9.8, 32.1)	10.8 (6.5, 14.5)	12.0 (8.1, 14.6)	0.0200
Two years OS	% (95% CI)	41.6 (29.9, 57.9)	22.9 (14.5, 36.2)	31.1 (23.6, 41.1)