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. 2024 Oct 18;15:8990. doi: 10.1038/s41467-024-53148-x

Table 1.

Summary of datasets used in Chakraborty et al. with hyperlinked references to the original paper

Species Reference Imaging modality Imaging
target
Use in Chakraborty et al. Strain Age (y or m) Sex (M:F)
Human HCP 7 T MRI White matter fiber bundles Gradient calculation, residual analysis (Figs. 28 and Supplementary Fig. S1S6) N/A 22-35 y 69:104
Resting-state BOLD signal
Human Kanel PET [18F]FEOBV Principal correlation analysis of structure-function tethering and cholinergic innervation (Figs. 4, 8) N/A 24.5 (4.9) y 10:3
Human Aghourian PET [18F]FEOBV Replication correlation analysis of structure-function tethering and cholinergic innervation (Supplementary Fig. S5) N/A 66.8 (6.8) y 5:13
Human Bedard PET [18F]FEOBV Replication analysis of structure-function tethering and cholinergic innervation (Supplementary Fig. S5) N/A 68.3 (3.1) y 4:1
Human Tuominen PET [18F]FEOBV Replication analysis of structure-function tethering and cholinergic innervation (Supplementary Fig. S5) N/A 37 (10.2) y 3:1
Mouse Li (SI Appendix Fig, 7) fMOST AAV-CAG-flex-GFP Unimodal versus transmodal cholinergic neuron branch counts with retrospective mouse data (Fig. 7 and Supplementary Fig. S7) ChAT-ires-Cre 3 m N/A
Mouse N/A microPET [18F]FEOBV Cross-validation of human cortical cholinergic innervation with prospective mouse data (Fig. 7 and Supplementary Fig. S7) VAChTflox/flox 6 m 3:3
Cross-validation of human cortical cholinergic innervation with prospective mouse data (Fig. 7 and Supplementary Fig. S7) C57BL/6 J 2:3

fMOST fluorescence micro-optical sectioning tomography, y   years, m   months, M   male, F   female. Ages are given as mean ±SD, where applicable.