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. 2024 Oct 17;15:8979. doi: 10.1038/s41467-024-53454-4

Fig. 8. Identification of the bacterial host of phages associated with response to FMT.

Fig. 8

A Alignment of FOCUS and LOTUS vOTUs of interest and their association with response across the different analyzes. Alignment was performed using Clustal Omega and a simplified representative diagram is shown. B Predictions of the host and lifestyle of the vOTUs of interest. Predictions were made using ipHOP and PhaBox. C Comparison of the raw counts of the LOTUS vOTUs of interest between the two donors. Donor 1 (n = 12) had higher FMT efficacy that donor 2 (n = 17) in the LOTUS trial. D Alignment of vOTUs of interest and long-read contig of interest (Contig_6261) to the genome of Oscillospiraceae CE91-St42, isolated from a Japanese centenarian. Alignment and visualization were performed using Proksee. Source data are provided as a Source Data file.