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. 2024 Oct 16;6(10):e1164. doi: 10.1097/CCE.0000000000001164

Figure 1.

Figure 1.

Greater CD206+ macrophages and satellite cell (SC) abundance in vastus lateralis muscle biopsies from patients recovering from critical COVID-19. Quantification of macrophage populations in muscle from COVID survivors (n = 9, blue) compared with controls (n = 22, white) including total CD11b+ macrophages, CD11b+CD206+ (M2-like) macrophages, and CD11b+CD206– (M1-like) macrophages (A) with representative images of macrophages in muscle from a COVID survivor (B; white arrows indicating CD11b+ CD206+). Quantification of paired box 7 (Pax7)+/4′,6-diamidino-2-phenylindole+ SCs in muscle from COVID survivors (n = 9, blue) compared with controls (n = 22, white) including total SCs, SCs associated with type 1 muscle fibers, and SCs associated with type 2 muscle fibers (C) with representative images of SCs (D; white and blue arrows indicating SC with type 1 and SC with type 2, respectively). Pax7 data from a subset within the control (n = 15) has been previously published (38). Data are expressed as mean ± sd; p values determined by Mann-Whitney U test; *significance p ≤ 0.05. Images acquired at ×200, scale bar = 100 µm.