Figure 8.

Top three rows indicate selected lead compounds, NTs they were conceived to target, and hence loop sequences incorporated into the warheads. Columns under each mimic then indicate the degree of correspondence to other NTs (m, mouse; h, human): highest correspondences have four colored residues; lowest have none. *5c(ii) was designed to mimic NT-3 with the loop (ii) sequence indicated in (PDB entry 1BND), i.e., TQNS. However, the literature consensus indicates this loop is in fact TGNS (UniProtKB: P20783).