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. Author manuscript; available in PMC: 2024 Oct 18.
Published in final edited form as: Sci Signal. 2024 Sep 24;17(855):eadn2616. doi: 10.1126/scisignal.adn2616

Figure 6. APP regulates JNK activation in response to proNGF in the axons.

Figure 6.

(A to F) Western blot analysis of total and phosphorylated (p-) JNK, APP and β-actin in BFCN axon lysates after axon stimulation with proNGF for 15 and 30 mins with or without (A to C) JNK inhibitor II or (D to F) APP siRNA application in the axons. Data are mean ± SEM, n = 6 (A to C) or 4 (D to F) independent experiments per treatment; *p < 0.05, p** < 0.01, ANOVA with Tukey’s multiple comparison tests.