Fig. 10.

Histidyl dipeptide levels are depleted in the atrophic gastrocnemius muscle. Levels of different histidyl dipeptides in the gastrocnemius and soleus muscles after 14 weeks of sham and transverse aortic constriction surgeries. Levels of (A) carnosine, (B) anserine, and (C) total histidyl dipeptides in the gastrocnemius muscle measured by LC–MS/MS. Levels of (D) carnosine, (E) anserine, and (F) total histidyl dipeptides in the soleus muscle. Data are presented as the mean ± SEM; n = 9–10 samples in each group; *p < 0.05 vs sham