Fig. 9.

Heart failure decreases the expression of aldehyde dehydrogenase (ALDH2) in the gastrocnemius muscle. Gastrocnemius muscles from C57BL/6J mice subjected to sham or transverse aortic constriction surgeries for 14 weeks were analyzed by Western blotting. Representative blots for (A) aldose reductase (AKR1B1) and (B) aldehyde dehydrogenase (ALDH2) are shown. (C) Bar graph shows the intensity of bands normalized to amido black (AB). Data are presented as the mean ± SEM; n = 5 samples in each group; *p = 0.04 vs sham