Table 1.
Echocardiographic parameters of mice subjected to sham or transverse aortic constriction surgeries for 14 weeks
| Parameters | Sham | TAC | p value |
|---|---|---|---|
| Body Mass (g) | 32.7 ± 1.62 | 30.9 ± 1.64 | 0.0198 |
| IVRT (ms) | 11.6 ± 1.5 | 16.1 ± 1.7 | 2E-06 |
| Heart Rate (BPM) | 544.2 ± 25 | 565 ± 53 | |
| LVESV (uL) | 16.6 ± 7.6 | 75.8 ± 43.6 | 0.0002 |
| LVEDV (uL) | 50.2 ± 13.7 | 99.8 ± 43.9 | 0.001 |
| SV (uL) | 33.6 ± 6.5 | 23.9 ± 13.0 | 0.0005 |
| Ejection Fraction (%) | 68.0 ± 5.7 | 28 ± 13.0 | 0.0001 |
| Cardiac Output (mL/min) | 18.3 ± 3.7 | 13.4 ± 2.1 | 0.0013 |
| LVAW;d (mm) | 1.1 ± 0.1 | 1.2 ± 0.1 | 0.5151 |
| LVAW;s (mm) | 1.7 ± 0.1 | 1.5 ± 0.1 | 0.0023 |
| LVID;d (mm) | 3.5 ± 0.3 | 4.8 ± 0.8 | 0.0001 |
| LVID;s (mm) | 2.0 ± 0.4 | 4.3 ± 1.0 | 0.0003 |
| FS (%) | 42.0 ± 6.3 | 13.0 ± 8.5 | 0.0001 |
Data are presented as the mean ± SEM, n = 10 samples in each group