Table 2.

Plasma coagulation times and bone marrow analysis, made on samples of C57BL/6 mice collected 1 hour after treatments with Vehicle, or two different doses of syngeneic EVs (3.3E09 EVs/Kg and 3.3E10 EVs/Kg). N=8; *: pVal<0.05 vs Vehicle by t -test.

Parameters	Vehicle	3.3E09 EVs/kg	3.3E10 EVs/kg
Fibrinogen (mg/dL)	111.00 ± 18.94	92.50 ± 25.29 *	58.75 ± 5.77 *
PT (sec)	71.65 ± 59.45	131.57 ± 68.37 *	136.27 ± 62.30 *
APTT (sec)	96.40 ± 51.37	197.55 ± 52.45 *	250.00 ± 0 *
Myeloid-erythroid ratio	1.45 ± 0.14	1.52 ± 0.13	0.17 ± 0.11 *
Proliferative erythroid pool (%)	12.11 ± 1.14	16.56 ± 1.29	14.76 ± 2.13
Proliferative myeloid pool (%)	12.19 ± 1.50	18.98 ± 0.77	23.02 ± 1.14 *
Lymphocytes (%)	9.78 ± 1.23	10.14 ± 0.60	8.31 ± 0.83