Table 2.

Prevalence and Prevalence Ratios for COPCs between ME/CFS (n = 595) and HC (n = 328)

			Unadjusted		Age Adjusted		Age and Sex Adjusted
		%	PR	95% CI	PR	95% CI	PR	95% CI
cMHA
ME/CFS	286	48.1	d4.15	3.04–5.66	d4.28	3.14–5.84	d4.19	3.07–5.72
HC	38	11.6	1.00	Referent	1.00	Referent	1.00	Referent
FM
ME/CFS	268	45.0	d147.74	20.83-1047.75	d138.12	19.47-979.75	d133.40	18.81-946.07
HC	1	0.3	1.00	Referent	1.00	Referent	1.00	Referent
cLBP
ME/CFS	197	33.1	d39.45	12.73-122.27	d37.15	11.98-115.21	d36.23	11.69-112.33
HC	3	0.9	1.00	Referent	1.00	Referent	1.00	Referent
IBS
ME/CFS	188	31.6	d6.91	4.16–11.49	d6.84	4.10-11.39	d6.76	4.06–11.25
HC	15	4.6	1.00	Referent	1.00	Referent	1.00	Referent
TMD
ME/CFS	82	13.8	d11.30	4.18–30.55	d10.98	4.05–29.76	d10.72	3.95–29.07
HC	4	1.2	1.00	Referent	1.00	Referent	1.00	Referent
IC/IB
ME/CFS	25	4.2	b13.78	1.88-101.24	a12.11	1.64–89.14	a11.16	1.51–82.18
HC	1	0.3	1.00	Referent	1.00	Referent	1.00	Referent
Any COPCs
ME/CFS	453	76.1	d4.58	3.60–5.82	d4.48	3.53–5.70	d4.38	3.45–5.57
HC	57	17.4	1.00	Referent	1.00	Referent	1.00	Referent

PR = prevalence ratio, 95% CI = 95% confidence interval

cMHA = chronic migraine/headache, FM = fibromyalgia, cLBP = chronic low back pain, IBS = irritable bowel syndrome, TMD = temporomandibular disorder, IC/IB = interstitial cystitis/irritable bladder, COPCs = chronic overlapping pain conditions

^ap < 0.05

^bp < 0.01

^cp < 0.001

^dp < 0.0001