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Schematic image of P. falciparum Kelch 13 protein with Plasmodium-specific sequence, a BTB–POZ domain, and 6 propeller domains. Locations of the oligonucleotide primers used in this study are indicated above the scheme (not to scale). Marker mutations validated (red) and candidate (blue) for artemisinin resistance [12] are shown below the scheme. Validated artemisinin-resistant mutations found in Uganda are enclosed within green boxes
