Table 2.
Characteristics | EA (n = 39) | Control Group (n = 19) | P | |||
---|---|---|---|---|---|---|
|
|
|
||||
Any Grade | Grade 3-4 | Any Grade | Grade 3-4 | Any Grade | Grade 3-4 | |
Any adverse event | 37 (94.87%) | 6 (15.38%) | 19 (100%) | 6 (31.58%) | 1.000a | 0.153b |
Leukopenia | 19 (48.72%) | 0 (0%) | 10 (52.63%) | 3 (15.79%) | 0.780b | 0.031 a |
Neutropenia | 22 (30.77%) | 1 (2.56%) | 13 (68.42%) | 5 (26.31%) | 0.380b | 0.012 a |
Thrombocytopenia | 7 (17.95%) | 0 (0%) | 2 (10.53%) | 0 (0%) | 0.703a | - |
Anemia | 14 (35.90%) | 0 (0%) | 9 (47.37%) | 0 (0%) | 0.402b | - |
ALT/AST increased | 11 (28.21%) | 0 (0%) | 9 (47.37%) | 0 (0%) | 0.150b | - |
Bilirubin increased | 2 (5.13%) | 0 (0%) | 0 (0%) | 0 (0%) | 1.000a | - |
Creatinine increased | 1 (2.56%) | 0 (0%) | 0 (0%) | 0 (0%) | 1.000a | - |
Nausea | 28 (71.79%) | 3 (7.69%) | 14 (73.68%) | 1 (5.26%) | 0.880b | 1.000a |
Vomiting | 13 (33.33%) | 3 (7.69%) | 10 (52.63%) | 2 (10.53%) | 0.159b | 1.000a |
Diarrhea | 16 (41.03%) | 2 (5.13%) | 4 (21.05%) | 0 (0%) | 0.155a | 1.000a |
Constipation | 2 (5.13%) | 0 (0%) | 1 (5.26%) | 0 (0%) | 1.000a | - |
Oral mucositis | 3 (7.69%) | 0 (0%) | 0 (0%) | 0 (0%) | 0.544a | - |
Foot-hand syndrome | 8 (20.51%) | 0 (0%) | 3 (15.79%) | 0 (0%) | 1.000a | - |
Peripheral sensory neuropathy | 18 (46.15%) | 0 (0%) | 9 (47.37%) | 0 (0%) | 0.931b | - |
Abbreviations: EA = electroacupuncture; ALT = alanine aminotransferase; AST = aspartate aminotransferase.
Significant differences are shown in bold.
Fisher’s exact test.
χ2 test.