Comparison of the OBP sites in the ori regions of alphaherpesviruses and roseoloviruses. OBP-binding regions of the oriLyts of alphaherpesviruses and roseoloviruses are shown. HSV1 L, HSV-1 oriL; HSV1 S, HSV-1 oriS; HSV2 L, HSV-2 oriL; HSV2 S, HSV-2 oriS; EHV1 S, equine herpesvirus 1 oriS; PRV, pseudorabies virus; VZV, varicella-zoster virus; MDV2, Marek's disease virus 2; I, II, and III, Box I, II, and III of HSV-1 oriS. Residues that match the HHV-7 consensus are shaded. Horizontal arrows indicate a structure with dyad symmetry in the HHV-7 sequence. The HHV-7 Box III-like sequence is underlined.