FIGURE 3.

Proteins that vary significantly with age via Spearman correlation. We ran Spearman correlations with chronological age on the concentrations of all 7008 proteins measured in our cohort of CDR = 0, Aβ‐ individuals. (a) 30% (2117) of all CSF proteins measured significantly correlated with age (p < 0.0001) while 70% (4891) of measured proteins showed no such relationship. (b) Three hundred and forty of the 1157 proteins used in our elastic net model to predict age were found to significantly correlate with chronological age. (c) A chart showing the full names, Entrez gene IDs and correlation values of the top 10 significant positively and negatively correlated proteins with chronological age.