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. 2024 Oct 14;17:7311–7324. doi: 10.2147/JIR.S472004

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© 2024 Zhu et al.

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EA inhibits inflammatory cytokine and chemokine expression in the DSS-induced colitis in mice. (A) Heat map showing the relative mRNA expression of inflammatory cytokines (Il1β, Il6, Infg, and Tnfa), chemotactic factors (Cxcl2, Cxcl9, and Ccl2), mpo, and Nos2 in the colonic tissue of Ctrl, DSS, DSS/EA-L, and DSS/EA-H groups of mice according to microarray analysis, n = 6. (B) Representative iNOS staining of colonic tissues of mice (upper scar bar: 250 µm, bottom scar bar: 50 µm). (C) ELISA of MPO, IL-1β, IL-6 and TNF-α levels in the serum of mice, n = 5. Data are expressed as the Mean ± SEM. *P < 0.05, **P< 0.01, ***P< 0.001; one-way ANOVA with Tukey’s post hoc analysis.