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. 2024 Oct 18;132(10):107005. doi: 10.1289/EHP14378

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Figure 3A is a forest plot titled Lasso, plotting amide herbicide metolachlor; neonicotinoid imidacloprid; carbamate carbendazim; organophosphate dimethyl thiophosphate; organochlorine beta-hexachlorocyclohexane; carboxamide herbicide diflufenican, organochlorine p,p′-dichlorodiphenyl dichloroethane; organochlorine alpha-hexachlorocyclohexane (y-axis) across percentage difference, ranging negative 10 to 15 in increments 5 (x-axis). Figure 3B is a forest plot titled Multipollutant ordinary least squares, plotting amide herbicide metolachlor; neonicotinoid imidacloprid; carbamate carbendazim; organophosphate dimethyl thiophosphate; organochlorine beta-hexachlorocyclohexane; carboxamide herbicide diflufenican, organochlorine p,p′-dichlorodiphenyl dichloroethane; organochlorine alpha-hexachlorocyclohexane (y-axis) across percentage difference (95 percent confidence intervals), ranging from negative 25 to 50 in increments of 25 (x-axis). — Percentage differences in hair 3,3′,5′-triiodothyronine (rT3) concentration per 2-SD increase in $log to the base 10$ -transformed pollutant (continuous variable; blue circle symbol) concentration or detect vs. nondetect (binary variable; dark blue square) in (A) the multipollutant lasso model or (B) the subsequent multipollutant OLS model on the pollutants stably selected by the lasso model among 196 healthy Chinese women of reproductive age. Models were adjusted for age, body mass index, and city. Symbols in (B) represent average percentage differences and lines represent 95% CIs. Numerical values are reported in Excel Tables S6 and S8. Note: AM, amide herbicide; CA, carbamate; CAR, carboxamide herbicide; CI, confidence interval; DDE, dichlorodiphenyl dichloroethane; DMTP, dimethyl thiophosphate; HCH, hexachlorocyclohexane; Lasso, least absolute shrinkage and selection operator; NE, neonicotinoid; OC, organochlorine; OLS, ordinary least squares; OP, organophosphate; SD, standard deviation.