Table 2.
Regression relationships between cognitive tests and ALPS‐index in the patients
| Cognitive test | Unstandardized beta | 95% confidence interval (lower–upper) | P‐value |
|---|---|---|---|
| Mini‐mental state examination | 30.689 | 6.419–54.958 | 0.014 |
| CASI total (100) | 94.463 | 5.404–183.522 | 0.039 |
| Mental manipulation (10) | 9.742 | −2.398–21.883 | 0.115 |
| Attention (8) | 5.895 | −1.204–12.994 | 0.103 |
| Orientation (18) | 17.460 | −2.126–37.045 | 0.121 |
| Long term memory (10) | 8.484 | −3.236–20.205 | 0.154 |
| Short term memory (12) | 15.703 | 2.635–28.770 | 0.019 |
| Abstract thinking (12) | 7.145 | −4.240–18.530 | 0.216 |
| Drawing ability (10) | 10.438 | 0.363–20.512 | 0.042 |
| Verbal fluency (10) | 9.470 | −1.090–20.031 | 0.078 |
| Language (10) | 10.155 | 0.705–19.606 | 0.035 |
Note: Dependent variable: Cognitive test score. Independent variables: ALPS‐index, education years and age.
Abbreviation: ALPS, diffusion tensor imaging along the perivascular space; CASI, Cognitive ability screening instrument, numbers in the parenthesis indicate maximal values.