Table 1.
Univariate and multivariate Cox regression of risk factors affecting the survival of GC patients
| Characteristics | Total(N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| Age | 367 | 1.620 (1.154–2.276) | 0.005 | 1.925 (1.326–2.794) | < 0.001 |
| <= 65 | 163 | ||||
| > 65 | 204 | ||||
| Gender | 370 | 1.267 (0.891–1.804) | 0.188 | ||
| Female | 133 | ||||
| Male | 237 | ||||
| Race | 320 | 1.248 (0.802–1.943) | 0.326 | ||
| Asian & Black or African American | 84 | ||||
| White | 236 | ||||
| Pathologic T stage | 362 | 1.719 (1.131–2.612) | 0.011 | 1.351 (0.855–2.135) | 0.197 |
| T1&T2 | 96 | ||||
| T3&T4 | 266 | ||||
| Pathologic N stage | 352 | 1.650 (1.182–2.302) | 0.003 | 1.486 (1.038–2.126) | 0.030 |
| N0&N1 | 204 | ||||
| N2&N3 | 148 | ||||
| Pathologic M stage | 352 | 2.254 (1.295–3.924) | 0.004 | 2.450 (1.314–4.566) | 0.005 |
| M0 | 327 | ||||
| M1 | 25 | ||||
| Histologic grade | 361 | 1.353 (0.957–1.914) | 0.087 | 1.366 (0.935–1.996) | 0.107 |
| G1&G2 | 144 | ||||
| G3 | 217 | ||||
| H pylori infection | 162 | 0.650 (0.279–1.513) | 0.317 | ||
| No | 144 | ||||
| Yes | 18 | ||||
| ACTL8 | 370 | 1.648 (1.055–2.254) | 0.003 | 1.446 (1.015–2.036) | 0.036 |
| Low | 183 | ||||
| High | 187 | ||||
Bold values are statistically significant (p < 0.05)