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. 2024 Oct 18;14:24502. doi: 10.1038/s41598-024-74109-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 9 — Drug sensitivity analysis of patients with high or low CD9 expression level. (a) Drug sensitivity of patients in high and low CD9 expression groups. Red indicates drugs with high sensitivity in patients with high CD9 expression, green indicates drugs with high sensitivity in patients with low CD9 expression, and gray indicates drugs with no sensitivity difference between high and low CD9 expression groups; (b) Correlation between drug IC50 and CD9. The top five drugs most negatively associated with CD9 are shown above, and the top five drugs most positively associated with CD9 are shown below. (c) IC50 values of the top5 drugs most positively and negatively correlated with CD9. The top 5 drugs most negatively correlated with CD9 are shown above, and the top 5 drugs most positively correlated with CD9 are shown below.