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Median TTF for both first CDK4/6i exposure and CDK4/6i retrial are shown in the table above. Below each cohort is the respective survival curves for CDK4/6i retrial. As noted before, median TTF for retrial in Cohort 1 is substantially longer than median TTF for initial exposure. This relationship is inverted for Cohorts 2 and 3, again speaking to the biological difference between Cohort 1 and Cohorts 2 and 3.
