Table 1.
Demographic information.
| Patient with major depressive disorder | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variables | Discovery set | Validation set | ||||||||
|
Depression
status (D) |
Remission status
with residual impairment (R1) |
Remission status
with
normal recovery (R0) |
p -value |
Depression status (D) |
Remission status with residual impairment (R1) | Remission status with normal recovery (R0) | p -value | |||
|
Number of participants |
10 | 9 | 6 | 25 | 17 | 13 | ||||
|
Age (mean ± SDa) |
61.9 ± 14.3 | 63.1 ± 12.3 | 62.0 ± 16.0 | 0.9799d | 47.8 ± 16.7 | 61.9 ± 13.0 | 60.8 ± 16.1 | 0.0083d | ||
|
Sex (male/female) |
2/8 | 1/8 | 0/6 | 6/19 | 4/13 | 1/12 | ||||
|
HAMD-17b (mean ± SD) |
21.7 ± 5.4 | 3.2 ± 2.9 | 3.2 ± 1.9 | 20.2 ± 4.3 | 3.5 ± 2.7 | 2.3 ± 1.7 | ||||
|
BMIc (mean ± SD) |
25.9 ± 3.3 | 23.8 ± 2.2 | 25.5 ± 5.6 | 0.4521d | 23.6 ± 3.1 | 24.1 ± 2.4 | 24.3 ± 4.0 | 0.7385e | ||
aSD, standard deviation; bHAMD-17, Hamilton depression rating scale (17-item); cBMI, body mass index; danalysis of variance (ANOVA) with Tukey’s multiple comparisons test (D vs. R1: p = 0.0155; D vs. R0: p = 0.0452 in validation set); eKruskal-Wallis test with Dunn’s multiple comparisons test.