Fig. 7.

Fibrocytes of the spiral ligament express high levels of Tnfrsf11b. All data are obtained from a 10-day-old Sprague-Dawley rat. ISH on sections through the inner and middle ear, with representative overview image and high magnification images of the spiral ligament lining the bony labyrinth of the inner ear and the tympanic bulla of the middle ear for (a)Tnfrsf11b and (b) Tnfsf11 ISH of an adjacent section. The green dashed line separates the fibrocytes of the spiral ligament from the bony labyrinth. The black dashed line separates bone protected from remodeling from bone undergoing remodeling. The red dashed line outlines a region of the tympanic bulla of the middle ear. Scale bars: overview = 1 mm, high magnification images = 50 µm. BL bony labyrinth, SL spiral ligament