Table 1.

Summary of binding constant K_d for T1R2/T1R3 with various sweet ligands

T1R2/T1R3	RebC	Rubusoside	RebM	RebD
TMD2 open (No C20)	340 µM	2.4 µM	190 nM
TMD3 open (No C20)	84 µM	3.0 µM	22 nM	2.8 nM
TMD2 open (+C20)	0.59 µM		0.28 nM
TMD3 open (+C20)	1.1 µM	26 nM	2.6 nM	46 pM