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. 2024 Oct 18;7:236. doi: 10.1038/s42004-024-01324-x

Table 2.

Summary of Hill slope nH for binding of various ligands to the human sweet receptor T1R2/T1R3

T1R2/T1R3 RebC Rubusoside RebM RebD
TMD2 open (No C20) 0.28 0.36 0.30
TMD3 open (No C20) 0.52 0.20 0.55 0.22
TMD2 open (+C20) 1.0 0.75
TMD3 open (+C20) 0.12 0.93 0.25 0.84