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. 2024 Oct 6;18(5):183–198. doi: 10.1049/syb2.12099

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© 2024 The Author(s). IET Systems Biology published by John Wiley & Sons Ltd on behalf of The Institution of Engineering and Technology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Acquisition of four crucial genes. (a) Venn diagram of upregulated differentially expressed genes (up‐DEGs) of single‐cell and 134 intersecting genes. (b–c) Differential expression of TSC22D1, ARMCX3, IGFBP5, and GGCT in PTC and normal (non‐PTC) epithelial cells. (d) Difference analysis results of 4 crucial genes based on included datasets. (e) Correlation analysis results of 4 crucial genes and Synaptojanin 2 (SYNJ2) based on included datasets. SYNJ2: synaptojanin 2 and PTC: papillary thyroid carcinoma.