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. 2024 Oct 19;8:236. doi: 10.1038/s41698-024-00734-3

Fig. 3. RNA sequencing findings of zccs1703.

Fig. 3

a Sashimi plot demonstrating altered splicing by the NF1 splice region variant (c.655-6 T > G). From top to bottom, tumour RNA of zccs1703, zccs1693 (pilocytic astrocytoma), zccs336 (pilocytic astrocytoma), zccs1580 (HGG H3 & IDH wildtype). b Relative expression of CD274 (PD-L1) (TPM) in this patient (zccs1703: red) compared to other HGG (high-grade glioma: blue) and all gliomas (cohort: black). c Relative expression of VEGFA (TPM) in this patient (zccs1703: red) compared to other HGG (blue) and all gliomas (cohort: black). TPM: transcript per million, HGG: high-grade glioma.