Table 1.

Detailed summary of behavioral assessment findings and statistics. Bold denotes significant effects following three-way ANOVA and post hoc comparisons between CD UNEXP, CD EXP, WD UNEXP, and WD EXP. Sample size = 14 rats/group (before outlier testing). Abbreviations: CD control diet, WD western diet, EPM elevated plus maze, SYM Social Y Maze, FPS fear-potentiated startle, ASR Acoustic Startle Reflex, SYM Social Y Maze, UNEXP Unexposed, WD Western Diet.

	ASR	FPS	EPM		SYM
	(% change from baseline)	(% FPS)	(% OA duration)	(Closed Arm Entries)	(# social interactions)	Frequency (Conspecific:Object)
Source of Variation	F Statistic, posthoc	F Statistic, posthoc	F Statistic, posthoc	F Statistic, posthoc	F Statistic, posthoc	F Statistic, posthoc
WD x PSS	F(1, 51) = 0.204, p = 0.6533	F(1, 34) = 0.034, p = 0.853	F(1, 52) = 1.731, p = 0.1941	F(1, 53) = 0.009, p = 0.9229	F(1, 50) = 0.442, p = 0.5088	F(1, 47) = 0.065, p = 0.7993
PSS	F(1, 51) = 4.708, p = 0.0347	F(1, 34) = 7.511, p = 0.009	F(1, 52) = 4.818, p = 0.0326	F(1, 53) = 0.3639, p = 0.5489	F(1, 50) = 5.293, p = 0.0256	F(1, 47) = 1.664, p = 0.2034
WD	F(1, 51) = 5.305, p = 0.0254	F(1, 34) = 0.008, p = 0.927	F(1, 52) = 15.89, p =0.0002	F(1, 53) = 0.0110, p = 0.9167	F(1, 50) = 5.168, p = 0.0273	F(1, 47) = 4.180, p = 0.0465
CDU vs WDU	p = 0.2306		p = 0.2467		p = 0.1882	p = 0.3829
CDU vs CDE	p = 0.6411	p = 0.0903	p = 0.9281		p = 0.1816	p = 0.7022
CDU vs WDE	p = 0.9997		p = 0.0004		p = 0.0134	p = 0.1048
WDU vs CDE	p = 0.0105		p = 0.5737		p > 0.9999	p = 0.9490
WDU vs WDE	p = 0.2372	p = 0.1530	p = 0.0672		p = 0.6421	p = 0.8809
CDE vs WDE	p = 0.5513		p = 0.0024		p = 0.6543	p = 0.5812