Table 5.
Comparison of antibody clones used for HER2 immunohistochemistry between IHC 0 and 1+ in surgical and biopsy specimen
| Antibody clone | Total (n=4,576) | Surgical specimen |
p-value | Total (n=2,810) | Biopsy specimen |
p-value | ||
|---|---|---|---|---|---|---|---|---|
| IHC 0 (%) | IHC 1+ (%) | IHC 0 (%) | IHC 1+ (%) | |||||
| Ventana | 4,366 | 2,676 (61.3) | 1,690 (38.7) | < 0.001 | 2,757 | 1,877 (68.1) | 880 (31.9) | < 0.001 |
| Dako | 210 | 67 (31.9) | 143 (68.1) | 53 | 15 (28.3) | 38 (71.7) | ||
Values are presented as number (%). HER2, human growth factor receptor 2; IHC, immunohistochemistry.