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EVs downregulate cytokine production in activated DC Human DC (n=10-11) after exposure to media alone (open circles), live Mf (closed circles) or EV (closed circles) were activated with LPS and IFN-y and supernatants assessed for production of IL-10 (A), IL-1a (B), IL-1b (C), RANTES (D), IL-8 (E), IL-12p40) (F), IL-12p70 (G), TNF-α (H). NS, non-significant.
