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. 2024 Aug 10;31(11):2440–2446. doi: 10.1093/jamia/ocae182

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© The Author(s) 2024. Published by Oxford University Press on behalf of the American Medical Informatics Association.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — Reproducible multimorbidity exploration analysis outline for schizophrenia. (A) Interactive Manhattan and scatter plot enable users to select top-co-occurred and consistent disease phenotypes. (B) Interactive table allows users to add or remove disease phenotypes by clicking on the rows in the table and incorporate the updated phenotypes into the final selection by clicking the Update Manhattan/Scatter button, highlighting the user-selected phenotypes. (C) Enhanced associationSubgraphs provides dynamic network analysis to explore disease clusters, highlighting the user-selected phenotypes from part A and B, and their corresponding subgraphs.