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. 2024 Jul 29;16(3):198–204. doi: 10.34172/ahj.1479

Figure 1.

Figure 1

An overview of the potential of apelin/APJ system in addiction. Interaction of mu receptor and apelin in lateral hypothalamus, as well as the heterodimerization of APJ and kappa opioid receptor (KOR), along with neuroprotective effects of apelin against drugs of abuse contribute to its potential involvement in addiction medicine