Table 2.
Demographic factors | pMCI | sMCI | p |
No. of patients | 8 | 37 | |
MCI subtype (EMCI/LMCI–/LMCI+) | 0/0/8 | 8/14/15 | 0.009 (df = 2) |
Age, y | 72.1±8.7 | 75.0±6.7 | 0.279 |
Sex (male/female) | 2/6 | 13/24 | 0.883 |
Education, y | 14.3±1.7 | 13.7±2.2 | 0.513 |
Baseline | |||
MMSE | 27.1±2.0 | 26.4±1.9 | 0.321 |
MoCA | 22.5±2.3 | 22.2±2.5 | 0.729 |
GDS-15 | 4.4±3.7 | 3.5±3.0 | 0.128 |
WMSR-LM Story A | 0.7±1.5 | 2.3±2.8 | 0.161 |
Duration of follow-up, months | 13.7±4.5 | 12.1±4.3 | 0.338 |
Use of anti-dementia medications (%) | 8 (100%) | 23 (62%) | 0.092 |
Average MMSE and MoCA score changes | –4.8±1.8 | 0.6±1.8 | <0.0001 |
AD score | 2.3±0.7 | 1.5±1.1 | 0.027 |
Values are shown as the mean±SD. MMSE, Mini-Mental State Examination, MoCA, Montreal Cognitive Assessment; WMSR-LM, Wechsler memory scale-revised – Logical Memory; GDS, Geriatric Depression Scale; pMCI, progressive MCI; sMCI, stable MCI; EMCI, early MCI; LMCI–, late MCI without AD brain imaging features; LMCI+, late MCI with AD brain imaging features; df, degrees of freedom.