TABLE 1.

Vaccine-elicited CTL responses^a

Vaccination and monkey	Tetramer binding		Functional cytotoxicity (stimulated PBMC)
	Fresh PBMC	Stimulated PBMC
Control MVA
H544	0.0	0	0
H547	0.0	0	1
H549	0.0	0	1
H561	0.0	0	0
Recombinant MVA
T119	0.5	17	37
H500	0.4	4	26
H507	0.2	39	61
H511	0.8	5	30

^aSIV Gag p11C-specific CD8⁺ T-cell responses as measured by tetramer staining of freshly isolated and peptide-stimulated PBMC and chromium release functional cytotoxicity assays at week 22, which is 1 week following the third immunization. The percent CD3⁺ CD8⁺ cells that bind tetramer is shown for the tetramer assays. The percent specific lysis at a 5:1 effector-to-target ratio is shown for the cytotoxicity assays.