TABLE 2.

CTL responses following challenge^a

Vaccination and monkey	Tetramer binding		Functional cytotoxicity (stimulated PBMC)
	Fresh PBMC	Stimulated PBMC
Control MVA
H544	0.1	2	2
H547	0.1	1	0
H549	0.7	19	22
H561	1.7	8	11
Recombinant MVA
T119	7.5	48	29
H500	3.9	49	37
H507	13.5	59	34
H511	2.5	42	28

^aSIV Gag p11C-specific CD8⁺ T-cell responses as measured by tetramer staining of freshly isolated and peptide-stimulated PBMC and chromium release functional cytotoxicity assays at day 17 after challenge. The percent CD3⁺ CD8⁺ cells that bind tetramer is shown for the tetramer assays. The percent specific lysis at a 5:1 effector-to-target ratio is shown for the cytotoxicity assays.