Table 2.
The univariate analysis between disease free survival (DFS) and clinicopathological characteristics
| Variables | Numbers | DFS (months) | 5-year survival (%) | 2 | value |
|---|---|---|---|---|---|
| Lauren classification | 41.731 | 0.001 | |||
| Diffuse type | 302 | 44.7 | 49 | ||
| Intestinal type | 436 | * | 67 | ||
| mixed type | 406 | 36.933 | 47 | ||
| Gender | 0.924 | 0.336 | |||
| Male | 846 | * | 54 | ||
| Female | 298 | * | 58 | ||
| Age | 19.242 | 0.001 | |||
| 45 years | 93 | * | 58 | ||
| 45–60 years | 631 | * | 60 | ||
| 60 years | 420 | 37.267 | 47 | ||
| Tumor site | 8.355 | 0.015 | |||
| Proximal | 466 | 49.267 | 49 | ||
| Middle | 376 | * | 61 | ||
| Distal | 302 | * | 56 | ||
| Tumor subtype | 84.799 | 0.001 | |||
| Non-infiltrating type | 196 | * | 83 | ||
| Borrmann type | 863 | 70.2 | 51 | ||
| Infiltrating type | 85 | 18.9 | 32 | ||
| Pathological classifications | 2.228 | 0.328 | |||
| Adenocarcinoma | 984 | * | 55 | ||
| Mucinous carcinoma | 107 | 68.633 | 51 | ||
| Signet ring carcinoma | 53 | 43.733 | 49 | ||
| Tumor size | 194.55 | 0.001 | |||
| 3 cm | 471 | * | 77 | ||
| 3–6 cm | 504 | 31.433 | 43 | ||
| 6 cm | 169 | 16.967 | 28 | ||
| Histopathology classification | 53.592 | 0.001 | |||
| Well differentiated | 27 | * | 96 | ||
| Moderately differentiated | 270 | * | 70 | ||
| Poor differentiated | 847 | 46.5 | 49 | ||
| Tumor infiltrating depth | 258.912 | 0.001 | |||
| T1 | 200 | * | 97 | ||
| T2 | 155 | * | 79 | ||
| T3 | 72 | * | 68 | ||
| T4 | 717 | 26.167 | 37 | ||
| Number of metastatic lymph nodes | 404.815 | 0.001 | |||
| N0 | 421 | * | 87 | ||
| N1 | 206 | 52 | |||
| N2 | 230 | 31.533 | 42 | ||
| N3 | 287 | 13.233 | 20 | ||
| Metastatic lymph nodes ration | 458.228 | 0.001 | |||
| 0 | 421 | * | 87 | ||
| 0.25 | 241 | * | 57 | ||
| 0.5 | 201 | 27.9 | 36 | ||
| 0.5 | 281 | 12.267 | 19 | ||
| AJCC 8th TNM stage | 382.954 | 0.001 | |||
| I | 268 | * | 96 | ||
| II | 261 | * | 72 | ||
| III | 615 | 19.7 | 31 | ||
| Vascular nerve infiltrating | 144.147 | 0.001 | |||
| Negative | 628 | * | 70 | ||
| Positive | 516 | 26.167 | 36 |
*The median survival time was not reached by follow-up, 0.05, statistical significance.