Table 3.
The univariate analysis between overall survival (OS) and clinicopathological characteristics
| Variables | Numbers | OS (months) | 5-year survival (%) | 2 | value |
|---|---|---|---|---|---|
| Lauren classification | 46.781 | 0.001 | |||
| Diffuse type | 302 | 62.633 | 51 | ||
| Intestinal type | 436 | * | 69 | ||
| Mixed type | 406 | 55.367 | 48 | ||
| Gender | 1.021 | 0.312 | |||
| Male | 846 | * | 55 | ||
| Female | 298 | * | 60 | ||
| Age | 19.161 | 0.001 | |||
| 45 years | 93 | * | 63 | ||
| 45–60 years | 631 | * | 61 | ||
| 60 years | 420 | 57.6 | 49 | ||
| Tumor site | 8.51 | 0.014 | |||
| Proximal | 466 | 65.3 | 51 | ||
| Middle | 376 | * | 62 | ||
| Distal | 302 | * | 59 | ||
| Tumor subtype | 82.088 | 0.001 | |||
| Non-infiltrating type | 196 | * | 86 | ||
| Borrmann type | 863 | 114.567 | 52 | ||
| Infiltrating type | 85 | 29.367 | 35 | ||
| Pathological classifications | 3.236 | 0.198 | |||
| Adenocarcinoma | 984 | * | 58 | ||
| Mucinous carcinoma | 107 | 70.133 | 53 | ||
| Signet ring carcinoma | 53 | 59.933 | 49 | ||
| Tumor size | 193.159 | 0.001 | |||
| 3 cm | 471 | * | 79 | ||
| 3–6 cm | 504 | 45.467 | 45 | ||
| 6 cm | 169 | 25.933 | 30 | ||
| Histopathology classification | 56.797 | 0.001 | |||
| Well differentiated | 27 | * | 96 | ||
| Moderately differentiated | 270 | * | 72 | ||
| Poor differentiated | 847 | 64.967 | 50 | ||
| Tumor infiltrating depth | 264.464 | 0.001 | |||
| T1 | 200 | * | 98 | ||
| T2 | 155 | * | 82 | ||
| T3 | 72 | * | 69 | ||
| T4 | 717 | 36.733 | 39 | ||
| Vascular nerve infiltrating | 145.628 | 0.001 | |||
| Negative | 628 | * | 72 | ||
| Positive | 516 | 36.367 | 38 | ||
| Number of metastatic lymph nodes | 412.207 | 0.001 | |||
| N0 | 421 | * | 88 | ||
| N1 | 206 | * | 56 | ||
| N2 | 230 | 43.7 | 44 | ||
| N3 | 287 | 20.233 | 22 | ||
| Metastatic lymph nodes ration | 462.637 | 0.001 | |||
| 0 | 421 | * | 88 | ||
| 0.25 | 241 | * | 60 | ||
| 0.5 | 201 | 37.267 | 40 | ||
| 0.5 | 281 | 20.433 | 19 | ||
| AJCC 8th TNM stage | 386.133 | 0.001 | |||
| I | 268 | * | 96 | ||
| II | 261 | * | 75 | ||
| III | 615 | 31.133 | 32 |
*The median survival time was not reached by follow-up, 0.05, statistical significance.