Table 7.

The COX risk model analysis of overall survival (OS) and disease-free survival (DFS) of miR-141-3p

Variables	Overall survival (OS)				Disease free survival (DFS)
	Univariate analysis	Multivariate analysis			Univariate analysis	Multivariate analysis
	$P$ value	HR	95%CI	$P$ value	$P$ value	HR	95%CI	$P$ value
Age	0.288				0.689
Gender	0.106				0.108
Tumor site	0.858				0.768
Tumor subtype	0.063				0.057
Pathological classifications	0.054				0.106
Tumor size	0.002	1.421	0.665–3.036	0.364	0.002	1.589	0.770–3.276	0.21
Histopathology classification	0.0503				0.062
Tumor infiltrating depth	0.001	1.95	0.709–5.364	0.196	0.001	1.974	0.770–5.061	0.157
Number of metastatic lymph nodes	0.001	1.488	0.867–2.555	0.149	0.001	1.508	0.877–2.592	0.138
Metastatic lymph nodes ration	0.001	0.217	0.065–0.729	0.013	0.001	0.244	0.084–0.705	0.009
AJCC 8th TNM stage	0.001	0.757	0.131–4.384	0.756	0.001	0.941	0.194–4.571	0.94
Vascular nerve infiltrating	0.007	0.971	0.448–2.106	0.942	0.009	0.899	0.430–1.878	0.776
adjuvant chemotherapy	0.346				0.196
Lauren classification	0.012	0.562	0.347–0.911	0.019	0.004	0.502	0.314–0.804	0.004
miR-141-3p	0.007	0.408	0.169–0.988	0.047	0.036	0.563	0.258–1.228	0.149

0.05, statistical significance.