Fig. 1. STD-NMR analysis of compound 1. (A) (a) 1H-NMR (blue) spectrum of compound 1 and (b) STD difference spectrum (red) of compound 1 recorded in the presence of protein. Relative saturation of protons normalized to that of H-6 is provided in the color codes (B) ribbon representation of USP7-CD with compound 1: hydrogen bonds: black color, aromatic hydrogen bond: red color, and π–π stacking interactions: blue color.
