IC₅₀ values of compounds 3a–h, 5a–d, and erlotinib against four cancer cell lines.

Comp.	Cell viability%	Antiproliferative activity IC50 ± SEM (nM)
		A-549	MCF-7	Panc-1	HT-29	Average (GI50)
3a	89	72 ± 7	69 ± 6	74 ± 7	74 ± 7	72
3b	90	70 ± 6	67 ± 6	70 ± 6	71 ± 6	70
3c	87	50 ± 5	46 ± 4	54 ± 5	52 ± 4	51
3d	89	76 ± 7	74 ± 7	76 ± 7	77 ± 7	76
3e	86	32 ± 3	31 ± 3	34 ± 3	34 ± 3	33
3f	90	62 ± 6	59 ± 5	65 ± 6	64 ± 6	63
3g	89	64 ± 6	60 ± 6	64 ± 6	66 ± 6	64
3h	85	82 ± 8	78 ± 7	86 ± 8	82 ± 8	82
5a	87	25 ± 2	23 ± 2	26 ± 2	26 ± 2	25
5b	90	39 ± 4	35 ± 4	41 ± 4	40 ± 3	39
5c	86	53 ± 5	49 ± 4	54 ± 5	55 ± 5	53
5d	90	46 ± 4	42 ± 4	48 ± 4	48 ± 4	46
Erlotinib	ND	30 ± 3	40 ± 3	30 ± 3	30 ± 3	33